Magnus and Will find themselves living as suburban neighbors with no knowledge of the Sanctuary. Will is a cardiac surgeon married to Abby, while Magnus is an artist. As time progresses, the two experience unsettling dreams where they are experimented in water tanks, while at the same time seeing several blue infinity symbols. When the dreams get worse, Will and Magnus suspect nothing is real. They also realise that whenever they attempt to escape, something keeps them in the dream world. To combat this, the two decide to commit suicide in the dream by driving a car over a cliff. They awaken back in reality to find themselves in one of Virgil St. Pierre's labs, where he and Henry work on a cure after Will and Magnus were poisoned by a large worm-like abnormal from Hollow Earth in Mexico. After hearing that several Sanctuary bases are on high alert since the incident and the one in Carentan, the team decide to return home.